6-Amino-8-(2-bromophenyl)-1,7,8,8a-tetrahydro-3H-isothiochromene-5,7,7-tricarbonitrile dimethylformamide solvate
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چکیده
منابع مشابه
6-Amino-8-(2-bromophenyl)-1,7,8,8a-tetrahydro-3H-isothiochromene-5,7,7-tricarbonitrile dimethylformamide solvate
In the title compound, C(18)H(13)BrN(4)S·C(3)H(7)NO, the thio-pyran ring and the adjacent six-numbered ring adopt distorted boat conformations. The mol-ecules, lying about inversion centers, form hydrogen-bonded dimers involving one of the H atoms on the amino group with the N atom of a cyano group of an adjacent mol-ecule, resulting in a 12-membered ring system [R(2) (2)(12) ring motif]. The o...
متن کاملSYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 6-CARBETHOXY-5-(3'-BROMOPHENYL)-3-ARYL-2-CYCLOHEXENONES AND 6-ARYL-4-(3'-BROMOPHENYL)-3-OXO-2,3A,4,5-TETRAHYDRO-2H-INDAZOLES
6-Carbethoxy-5-(3'-bromophenyl)-3-aryl-2-cyclohexenones 2a-j were obtained from the1-Aryl-3-(3'-bromophenyl)-2-propene-1-ones 1a-j by Micheal addition of ethyl acetoacetate, followed by internal Claisen condensation. Reaction of 2a-j with hydrazine hydrate afforded the corresponding 6-Aryl-4-(3'-bromophenyl)-3-oxo-2,3a,4,5-tetrahydro-2H-indazoles 3a-j. The structures of newly synthesized compou...
متن کاملCyclo(l-tyrosyl-l-tryptophanyl) dimethylformamide solvate
THE STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: (3S,6S)-3-(4-hydroxy-benz-yl)-6-(1H-indol-3-ylmeth-yl)piperazine-2,5-dione dimethyl-formamide solvate], C(20)H(19)N(3)O(3)·C(3)H(7)NO, contains hydrogen-bonded tapes typical for diketopiperazines. The structure is stabilized by strong inter-molecular inter-actions of the types O-H⋯O and N-H⋯O involving the dipeptide and the solvent mol-ecule...
متن کامل3,5a,9-Trimethyl-8-(2-phenylhydrazin-1-ylidene)-4,5,5a,9b-tetrahydro-3aH,8H-naphtho[1,2-b]furan-2(3H)-one
The title compound, C(21)H(24)N(2)O(2), is a phenyl hydrazine derivative of the well known anthelminthic agent α-santonin, which is composed of three fused rings (benzodieneone, cyclo-hexane and γ-lactone). The cyclo-hexa-dienone ring adopts a boat conformation, the cyclo-hexane ring is in a chair conformation and the trans-fused γ-lactone ring adopts a C-envelope conformation. In the crystal, ...
متن کامل(E)-6-Amino-1,3-dimethyl-5-[(pyridin-2-ylmethylidene)amino]pyrimidine-2,4(1H,3H)-dione
In the title compound, C(12)H(13)N(5)O(2), a Schiff-base-derived chelate ligand, the non-aromatic heterocycle and its substituents essentially occupy one common plane (r.m.s. of fitted non-H atoms = 0.0503 Å). The N=C bond is E-configured. Intra-cyclic angles in the pyridine moiety cover the range 117.6 (2)-124.1 (2)°. Intra- and inter-molecular N-H⋯N and N-H⋯O hydrogen bonds are observed in th...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2009
ISSN: 1600-5368
DOI: 10.1107/s1600536809039105